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Effects of Ionizing Radiation on Human 3D Vessel Models

Posted By Administration, Wednesday, February 2, 2011
Updated: Monday, April 22, 2013

This month’s podcast includes an interview with Drs. Peter Grabham and Charles Geard fromColumbia University, who discuss their article: "Effects of Ionizing Radiation on Three-Dimensional Human Vessel Models: Differential Effects Accordingto Radiation Quality and Cellular Development”.

Vered’s News Minute is about a group of British schoolchildren who may be the youngest scientists ever to have their work published in a peer-reviewed journal.

Happy listening!

Tags:  3D cell culture  cardiovascular effects 

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Late Health Effects on Ionizing Radiation

Posted By Administration, Wednesday, December 15, 2010
Updated: Monday, April 22, 2013

This podcast number is published in memoriam of Elaine Ron, who passed away on November 20, 2010. A special issue of Radiation Research was published this month with a selection of papers presented at the Conference "Late Health Effects of Ionizing Radiation: Bridging the Experimental and Epidemiologic Divide” that was held in Washington DC, in May 2009. Massimo interviews Peter Jacob, co-author with Elaine Ron of the paper that introduces the special issue.


Vered’s News Minute focuses on the most affordable particle accelerator: a strip of Scotch tape!

Our November interview is on its way to publication and will appear shortly. And so is a Special December issue! Stay tuned.

 Attached Thumbnails:

Tags:  cancer risk  epidemiology 

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p53 Inhibition with Pifithrin Alpha

Posted By Administration, Friday, December 10, 2010
Updated: Monday, April 22, 2013

Welcome to the November 2010 issue of the Radiation Research podcast, featuring the interview with Ingeborg Tinhofer, the final author of the paper entitled Pifithrin-α as a Potential Cytoprotective Agent in Radiotherapy: Protection of Normal Tissue without Decreasing Therapeutic Efficacy in Glioma Cells.

Inge Tinhofer’s research team: Inge Tinhofer (third from the left), first author Brigitte Sinn (third from the right)

Tags:  tumor radiosensitization 

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Fractionated Radiation Therapy Can Induce a Molecular Profile for Therapeutic Targeting

Posted By Administration, Saturday, December 4, 2010
Updated: Monday, April 22, 2013

Sylvain Costes interviews Drs. John-Aryankalayil and Palayoor, scientists from the Coleman Laboratory at the NCI, Radiation Oncology Branch, Bethesda, USA. They discuss how gene expression profiles of two different prostate carcinoma cells reveal distinct responses between acute and fractionated radiation exposures. The abstract of the manuscript can be found here.

Tags:  microarray  radiotherapy 

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Effects of Ionizing Radiation on Cell-to-Cell Communication

Posted By Administration, Saturday, December 4, 2010
Updated: Monday, April 22, 2013

Sylvain Costes interviews Drs. Luca Mariotti and Andrea Ottolenghi, from the department of nuclear physics and theory in Pavia, Italy. The discussion is centered on a mathematical framework for understanding the impact of intercellular signaling on bystander phenomena observed after exposure to ionizing radiation. The abstract of the paper can be found here.

Tags:  Bystander effects  cytokine signaling  Modeling  non-targeted effects 

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Bystander Adaptation in 3D

Posted By Administration, Wednesday, September 22, 2010
Updated: Monday, April 22, 2013

Welcome to the August 2010 issue of the Radiation Research Podcast. In this month’s issue, Vered Anzenberg’s News Minute focuses on educating immune cells with salmonella against melanoma.

 

Authors of the featured paper: Edouard Azzam (left photo), Massimo Pinto and Roger Howell (right photo).

The interview of the month is curated by Marjan Boerma, who spoke to the authors of the paper entitled Investigation of Adaptive Responses in Bystander Cells in 3D Cultures Containing Tritium-Labeled and Unlabeled Normal Human Fibroblasts.

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Tags:  3D cell culture  adaptive responses  Bystander effects 

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Image-Guided Micro-Irradiation

Posted By Administration, Monday, August 23, 2010
Updated: Monday, April 22, 2013

Drs. Debabrata Saha and Timothy D. Solberg from the Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas, are interviewed about their work.Our conversation is based on their article published in the July issue of Radiation Research: An Orthotopic Lung Tumor Model for Image-Guided Microirradiation in Rats

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The Golden Age for Radiotherapy?

Posted By Administration, Wednesday, June 23, 2010
Updated: Monday, April 22, 2013

Drs. Devika B. Chithrani and David A. Jaffray from the Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada are interviewed about their work on novel approaches to radiosensitize cells.Our conversation is based on their article published in the June issue of Radiation Research: Gold Nanoparticles as Radiation Sensitizers in Cancer Therapy.

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How Do Mitochondrial Mutant Cells Respond to Radiation?

Posted By Administration, Friday, June 11, 2010
Updated: Monday, April 22, 2013

This months "News Minute with Vered” focuses on the odd story of the classification of the tomato as a vegetable.

Drs. Rohan Kulkarni and James Tucker are interviewed about their work on the response of mitochondrial mutant cells to genotoxic stresses such as ionizing radiation.Our conversation is based on their article published in the May issue of Radiation Research: Mitochondrial Gene Expression Changes in Normal and Mitochondrial Mutant Cells after Exposure to Ionizing Radiation.

Tags:  mitochondria  radiation damage 

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Microvessel Damage

Posted By Administration, Thursday, June 10, 2010
Updated: Monday, April 22, 2013

This months "News Minute with Vered” covers up the story of the origin of the Lab coat, and its colour.

Dr. Xiao Wen Mao was interviewed about their work on the response of micro vessels in the hippocampus after high-LET radiation.The conversation is based on their article published in the April issue of Radiation Research: High-LET radiation-induced response of microvessels in the Hippocampus.

 

Authors of this month’s article:
Xiao Wen Mao (pictured in the center), Cecile J. Favre (right), John R. Fike, Lucie Kubinova, Ella Anderson, Mary Campbell-Beachler, Tamako Jones, Anna Smith, Steven Rightnar, and Gregory A. Nelson (pictured left)

Tags:  High-LET 

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