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TENTATIVE PROGRAM: Monday, October 16
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CME
Non-CME Poster Session Networking
7:30am - 8:00am  Registration Open, Coffee Break with Exhibitors
8:00am - 8:50am  Topical Review 5: Harnessing redox biology for improving cancer therapy outcomes while protecting normal tissue: Douglas Spitz
 Topical Review 6: Can radiobiology input into (proton) treatment planning in the personalized medicine era: Harald Paganetti
 Topical Review 7: Cell death: basic concepts and common misconceptions: Lorenzo Galluzi
 Topical Review 8: Radiation archives and datasets for solving new questions in radiation biology: Gayle Woloschak
9:00am - 10:00am  Plenary 2: Genomics in the era of advanced radiotherapy: Catharine West
10:00am - 10:15am  Coffee Break with Exhibitors
10:15am - 12:15pm  Symposium 11: RRS/COSPAR joint symposium: The future of space missions
  Chairs:
David Chen, Katherine Castle
  • Radiation shielding for human deep space missions: John Norbury
  • Future opportunities for radiation research on China Space Station and our progress on cytoskeleton-centered radiobiological studies: Guangming Zhou
  • The training and space missions of a NASA astronaut: Captain Christopher Cassidy, PhD, MS
  • Differential effects on murine intestinal epithelial cell migration is dependent on radiation quality: Santosh Kumar
  • Influence of sex on lung cancer development after HZE exposure in genetically engineered mouse model: Katherine Castle
 Symposium 12: Role of innate immune cells in the response to radiation
  Chairs:
Sanda Demaria, Nils-Petter Rudqvist
  • Radiation-induced cancer cell immunogenicity is mediated by cytosolic dsDNA activation of cGAS/STING pathway and regulated by Trex1: Sandra Demaria
  • Exploiting natural killer cells to potentiate radiation-induced anti-tumor immunity: Karsten Pilones
  • TBD: Marka Crittenden
  • TBD: Arta Monir Monjazeb
 Symposium 13: Chromatin remodelling
  Chair:
Amy Kronenberg
  • Heterochromatin as a phase-separated system and how it intersects with DNA DSB repair: Amy Strom
  • Radiation-induced activation of innate immunity from errors in mitosis: Samuel Bakhoum
  • Specificity in the response of the mammalian methylome to ionizing radiation: Mitchell Turker
  • Ago1 promotes histone H3K9 methylation to coordinate transcriptional silencing and 53BP1 repositioning at DNA double-strand breaks: Michael Hendzel
 Symposium 14: The potential of nanoparticles: How sophisticated can we get and what is the potential for clinical translation?
  Chair:
Jan Schuemann
  • Nanoparticles for tumor imaging: James W. Tunnell
  • Nuclear-localized gold nanoparticles potently sensitize cells to radiation across a spectrum of energies and LETs: Maureen Aliru
  • How can NPs go clinical, hunting the latest advances or focus on 'boring' NPs? What can we expect in the clinic to assist radiation therapy?: Jan Schuemann
12:15pm - 1:45pm  Business Forum (Members only, RSVP required)
1:45pm - 2:30pm  Poster Session 3 - Normal tissue radiation responses
2:30pm - 3:15pm

 Poster Session 4 - DNA and oxidative damage responses
                              - Cell and tissue kinetics/signaling/microenvironment

3:15pm - 5:15pm  Symposium 15: Prostate cancer genomics and targeting to improve radiotherapy
  Chair:
Robert Bristow
  • DNA repair gene mutations and prostate cancer: risk and aggression: Peter Nelson
  • Signatures of prostate cancer radiotherapy outcome- where are we now?: Felix Feng
  • Combining genetics and the microenvironment for prostate cancer treatment decisions: Robert Bristow
  • Identifying a novel molecular switch of the radiation response of prostate cancer cells: Laure Marignol
 Symposium 16: Radiation and circulatory disease
  Chairs:
Carmen Bergom, Marjan Boerma
  • Circulatory disease associated with low and moderate ionizing radiation exposure - a summary of the epidemiological evidence: Mark Little
  • Multiple organ injury after irradiation induces cardiac remodeling with functional changes: Meetha Medhora
  • Cardiovascular sequelae of childhood cancer therapy and implications for adult health: Daniel A. Mulrooney
  •  Human ghrelin mitigates vascular leakage and endothelial cell pyroptosis in mice exposed to total body irradiation: Weng-Lang Yang
 Symposium 17: Radiation-drug combinations to improve clinical outcome and reduce normal tissue toxicity
   Chair:
Pat Prasanna
  • Challenges in developing drug radiation combinations: Richard Amos
  • Changing the standard of care in medicine: The bumpy road from the bench to the clinic: Yaccov Lawrence
  • Redefining dose to enhance post-treatment quality of life: Jeff Buchsbaum
  • Repurposing disulfiram for selective hypoxic cancer cell toxicity and radio-chemo-sensitization in lung cancer: Kelly Falls
  • Antibody drug conjugate targeted radiosensitization: Sunil Advani
 Symposium 18: Signaling and therapy for combined radiation injury
  Chairs:
Juliann Kiang, Evagelia Laiakis
  • Ghrelin therapy increases survival & corrects the cytokine-AKT-MAPK signaling network after irradiation combined with wound trauma: Juliann Kiang
  • Age and time: major factors in treatment approaches to radiation combined injury: Jacqueline Williams
  • Macrophage response to radiation and virus exposure: cytokine and chemokine production and cell signaling control: R. Joel Lowy
  • Mitigation of combined injuries by angiotensin converting enzyme (ACE) inhibitors: John Moulder
5:15pm - 5:30pm  Coffee Break with Exhibitors
5:30pm - 6:00pm  Michael Fry Award Lecture - Igor Koturbash: When DNA is actually not a target: radiation epigenetics as a tool to understand and control cellular response to ionizing radiation
6:00pm - 6:30pm
 Marie Curie Award Lecture- Nils-Petter Rudvqist: The TCR repertoire of tumor-infiltrating T cells is shaped by treatment with radiotherapy and anti-CTLA-4 and includes shared and  unique clonotypes



  RADIATION RESEARCH SOCIETY
380 Ice Center Lane, Suite C | Bozeman, MT 59718 | 1.877.216.1919
Member & Exhibitor Services: Audrey Rinehart |
1.877.216.1919  |  audrey@radres.org