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TENTATIVE SCHEDULE - Sunday, October 15
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CME
Non-CME Poster Session Networking
7:30am - 8:00am
 Registration Open, Coffee Break with Exhibitors
8:00am - 8:50am  Topical Review 1: Masterclass in the physics of cell irradiation for the non-expert: Mark Hill
 Topical Review 2: The inflammatory nexus in radiation responses: Dorthe Schaue
 Topical Review 3: Do we now have the biomarkers to predict radiotherapy-induced normal tissue toxicity: Olga Martin
 Topical Review 4: Preclinical models for advanced radiotherapy: Karl Butterworth
9:00am - 10:00am
 Plenary 1: Innovations in radiation medicine- can we take collaboration to the next level?: David Jaffray
10:00am - 10:15am  Coffee Break with Exhibitors
10:15am - 12:15pm  Symposium 1: Cancer therapies and CTCs
  Chairs: Olga Martin & Mary-Keara Boss
  • Circulating tumour cells, cancer therapies and metastasis: Michael MacManus
  • The new role of histone H2AX in EMT and metastasis: deciphering beyond DNA repair: Urbain Weyemi
  • High resolution intravital microscopy reveal the dynamics and interaction of tumour cells: Maria Alieva
  • Effects of radiation on recruitment of trafficking cancer and immune cells: Edward Graves
 Symposium 2: The RBE of proton beam therapy and its clinical significance
  Chairs:
Henning Willers, Antino Allen
  • Introduction - Toward a variable proton RBE for tumor and normal tissues: Henning Willers
  • Repair of DNA damage caused by particle radiation: Claudia Wiese
  • Modeling and predicting the relative biological effectiveness of proton beam therapy: Stephen McMahon
  • Experimental approaches for determining RBE in-vitro and in-vivo: Claere Von Neubeck
  • Towards clinical evidence for a variable proton RBE: David Grosshans
   Symposium 3: The chemistry of DNA damage, repair and molecular radiotherapy
  Chairs:
David Close & Don Jones
  • Free radical mechanisms of radiation damage to DNA: Michael Sevilla
  • Examining DNA oxidation via independent generation of nucleobase reactive intermediates: Marc Greenberg
  • Electron-Induced Site-Specific Formation and Reactions of Aminyl Radicals in Azido-Nucleic Acid Models: Amitava Adhikary
  • Targeted radionuclide therapy: the chemistry driving efficacy and safety: Rebecca Abergel
 Symposium 4: Synthetic lethality revisited: Tumor-selective use of PARP inhibitors for anti-cancer therapy
  Chair:
David Boothman
  • A novel regulator complex is involved in resistance to PARP inhibitor: Zihua Gong
  • Leveraging use of NQO1 bioactivatable drugs for tumor-selective anticancer therapy: Xiumei Huang
  • Loss of RPRD1B/K-H leads to BRCAness and PARP inhibitor hypersensitivity: Edward Motea
  • TBD: Ashley Schlafstein
  • XRN2 depletion is synthetic lethal with PARP1 inhibition in specific cancers: David Boothman
 Symposium 5: Therapeutic radiation induced delayed vascular complications
  Chairs:
Mohan Natarajan, Janice Zawaski
  • Radiation-induced microvascular injury as a mechanism of salivary gland hypo function: Adriana Haimovitz-Friedman
  • Vascular mediated normal tissue damage and contemporary preventive strategies: Martin Hauer-Jensen
  • Influence of mechanotransduction signaling on radiation induced vascular gene modification: Natarajan Aravindan
  • The NIAID radiation nuclear countermeasure program: update on challenges in the field of radiation-induced endovascular injury: Merriline Satyamitra
  • A radiation augmented multimodal nanotherapeutic approach for targeting the tumor endothelium in Triple Negative Breast Cancer: Meenakshi Upreti
12:15pm - 1:45pm  SIT Lunch (SITs only, RSVP Required)
1:45pm - 2:30pm  Poster Session 1 - Experimental therapeutics/radiotherapy/translational research
2:30pm - 3:15pm  Poster Session 2 - Experimental therapeutics/radiotherapy/translational research
                               - Epidemiology of cancer and non-cancer diseases
3:15pm - 5:15pm  Symposium 6: Harnessing the power of metabolism to improve radiation therapy
  Chairs:
Robert Griffin & Igor Koturbash
  • New stable tracer approaches to measure human metabolism: Nicolaas E Deutz
  • Metabolomic biomarkers predictive of late effects of radiotherapy: Amrita Cheema
  • Local radiotherapy potentiates the anticancer effects of methionine deficiency by targeting one-carbon metabolism and Mat2a down-regulation: Igor Koturbash
  • Enhancement of radiation response in breast cancer stem cells by inhibition of thioredoxin and glutathione dependent metabolism: Melissa Fath
  • Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines: Gunnar Boysen
   Symposium 7: Space radiation and normal tissue injury
  Chair:
Chiara LaTessa
  • Enhanced pattern separation following space radiation exposure in maturity: neural and molecular underpinnings: Amelia Eisch
  • Late effects (or not) of 56Fe radiation on physical and cognitive health, neuroinflammation and Alzheimer's pathology in male and female mice: Cynthia Lemere
  • The effect age-associated mismatch repair defects on hematopoietic function in the face of cosmic radiation: Scott Welford
  • European efforts in space radiation dosimetry onboard the International Space Station and beyond: Thomas Berger
  • Characterization of innovative shielding materials for radio protection in deep-space travels: Marta Rovituso
 Symposium 8: Low dose radiation responses and implications for risk
  Chair:
Tatjana Paunesku
  • Biological consequences of low level exposures: the impact of radiation dose, dose-rate, and quality: Edouard Azzam
  • The role of secondary excitation decay and exosomes in the generation of bystander effects: Carmel Mothersill
  • Low dose response to ionising radiation and its role in cataractogenesis: Munira Kadhim
  • Risk projections for exposures to low dose rate radiation: a paradigm shift?: David Pawel
 Symposium 9: Pioneering radiobiology - then and now: A history symposium to honor Jack Fowler and Sir Oliver Scott
  Chairs:
Howard Lieberman, Colin Seymour
  • Gray but not bland: Colin Seymour
  • Jack Fowler: Scientist, mentor, sponsor: Elizabeth Travis
  • Modulation of oxidative stress influences tumor response to radiotherapy: Mary-Keara Boss
  • TBD: Soren Bentzen
  Symposium 10: Stem cell biology and radiotherapy
  Chair: Tej Pandita
 
  • Stem cell factor MOF is critical for DNA damage repair: Tej Pandita
  • Role of environmental signals in salivary gland stem cell self-renewal and radiation response: Robert P. Coppes
  • Epigenetic mechanisms of cellular plasticity in response to injury: John P. Cooke
  • DNA damage response decreases during human stem cell differentiation: Kalpana Mujoo
5:15pm - 5:30pm  Coffee Break with Exhibitors
5:30pm - 6:30pm  Failla Lecture: Radiation, risk, and randomness- Dale Preston
6:45pm - 8:45pm  Welcome Reception- Sponsored by Xstrahl
8:30pm - 11:30pm  Karaoke
 



  RADIATION RESEARCH SOCIETY
380 Ice Center Lane, Suite C | Bozeman, MT 59718 | 1.877.216.1919
Member & Exhibitor Services: Audrey Rinehart |
1.877.216.1919  |  audrey@radres.org