|Debate: Sunday, September 21, 2014|
D1: Is the Abscopal (out-of-field) Effect Important to Curing Cancer with Radiation Therapy?
|D2: Are There Viable Mitigators of Radiation Effects?|
Garry R. Buettner, PhD: PLENARY SPEAKER
Buettner is a Professor in the Free Radical and Radiation Biology
Program/Department of Radiation Oncology at The University of Iowa. His
research focuses on the flow of electrons through chemical, biochemical, and
biological systems and the consequences of changing the current in different
biological circuits. In mitochondria electrons flow through a high flux
circuit efficiently producing ATP, and H2O (respiration). However,
some electrons do not flow to dioxygen, rather just to NAD+
(glycolysis). Of special interest is the flow of electrons into the many
low flux biochemical circuits that partially reduce dioxygen producing
superoxide and hydrogen peroxide. Understanding quantitatively the
elements of these circuits (e.g. antioxidants, redox
enzymes, and proteins) and how they dictate the fundamental biology of cells
and tissues and overall health of organisms is the primary goal. Using
this information to improve human health is the ultimate reward.
Nicholas Dainiak, MD, FACP: PLENARY SPEAKER
M.D., F.A.C.P. is a graduate of Fairfield University and Loyola-Stritch School
of Medicine. He trained in Internal
Medicine at Albany Medical Center and in Hematology at Yale University School
of Medicine. He rose to the rank of
Professor of Medicine at Tufts University, and became Scientific Director of the
Stem Cell Transplant Program and then Director of the Connecticut Cancer
Institute at the University of Connecticut Health Center. He was recruited to McGill as the Louis
Lowenstein Chair of Hematology/Oncology and Chief of Hematology/Oncology at the
Royal Victoria Hospital, Montreal. He returned
to Connecticut in 1995 where he served as Chairman of Medicine for 18 years at
Yale New Haven Health–Bridgeport Hospital.
He is Clinical Professor of Internal Medicine and of Therapeutic
Radiology (pending) at Yale. READ MORE...
Marco Durante, PhD
Marco Durante was appointed as the Director of the Biophysics Department at GSI Helmholtz Center (Darmstadt, Germany) in October 2008 and is now also Full Professor at the Technical University of Darmstadt (Germany) and Adjunct Professor at the Temple University, Philadelphia (PA, USA), the Frankfurt Institute for Advanced Studies (FIAS, Germany), and at the Gunma College of Medicine (Japan). He previously served as Associate Professor of Physics at the University of Naples Federico II (Italy). READ MORE...
Kenneth Kinzler, PhD
Kenneth Kinzler, Ph.D., is Professor of Oncology at The Sidney Kimmel Comprehensive Cancer Center (SKCCC) at the Johns Hopkins University School of Medicine is co-director of the Ludwig Center at Johns Hopkins University.. He has produced classic studies of the genes causing human cancer including the discovery of APC, the gene that initiates virtually all colorectal tumors. His subsequent analyses of the functional properties of the APC gene product have had widespread ramifications for developmental biology as well as cancer biology. He is also known for his development of genetic methods for analyzing gene expression and mutations in human cancer leading to his most recent work on defining the cancer genome for more than a dozen human tumor types. He has coauthored over 350 peer-reviewed articles on the molecular analyses of cancer.
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