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RRS Conversations with Jan Schuemann

Posted By Administration, Tuesday, January 22, 2019
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Interview with Michael Scholtz

Posted By Administration, Tuesday, January 29, 2013
Updated: Monday, April 22, 2013

 

The November 2012 podcast features an interview with Michel Scholtz from GSI Darmstadt, Germany, senior author of the paper entitled Modeling Cell Survival after Photon Irradiation Based on Double-Strand Break Clustering in Megabase Pair Chromatin Loops appearing in the November 2012 issue of Radiation Research. The interview is hosted by Massimo Pinto and touches on the research efforts of Michael Scholtz, and his colleagues, who have been focused for a long time toward a deeper understanding of the biological effects of high linear energy transfer radiations that are used in cancer therapy with accelerated ion beams. Their more recent work that Michael Scholtz describes in this interview focuses on modeling the biological impact of clustered vs isolated DNA double strand breaks induced by photon irradiation, as a means to better understand some complexities that have emerged in their earlier investigations with high-LET radiation.

Tags:  DNA damage  DNA repair  Modeling 

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Effects of Ionizing Radiation on Cell-to-Cell Communication

Posted By Administration, Saturday, December 4, 2010
Updated: Monday, April 22, 2013

Sylvain Costes interviews Drs. Luca Mariotti and Andrea Ottolenghi, from the department of nuclear physics and theory in Pavia, Italy. The discussion is centered on a mathematical framework for understanding the impact of intercellular signaling on bystander phenomena observed after exposure to ionizing radiation. The abstract of the paper can be found here.

Tags:  Bystander effects  cytokine signaling  Modeling  non-targeted effects 

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