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News & Press: Radiation News

Drug-based approach sensitizes hypoxic tumors to radiation therapy

Saturday, April 6, 2019  
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Drug-based approach sensitizes hypoxic tumors to radiation therapy

Hypoxia exists to some degree in most solid tumors due to inadequate oxygen delivery of the abnormal vasculature which cannot meet the demands of the rapidly proliferating cancer cells. The levels of oxygenation within the same tumor are highly variable from one area to another and can change over time. Tumor hypoxia is an important impediment to effective cancer therapy.

The approved drug papaverine can be used to increase oxygen levels in mouse tumor models — making them more sensitive to radiation therapy.

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