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News & Press: Radiation News

150-year-old drug may improve radiation therapy study

Wednesday, April 24, 2019  
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150-year-old drug may improve radiation therapy study

A drug first identified 150 years ago and used as a smooth-muscle relaxant could make tumours more sensitive to radiation therapy, according to a study. Researchers from Ohio State University (OSU) in the US found that the drug called papaverine, inhibits the respiration of mitochondria, the oxygen-consuming and energy-making components of cells, and sensitises model tumours to radiation. The study, published in the journal Proceedings of the National Academy of Sciences, found that the drug does not affect the radiation sensitivity of well-oxygenated normal tissues.

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